Products

Autotaxin Axin Beta-catenin γ-secretase Dishevelled Dkk-1 Frizzled Gli Hippo Notch Porcupine Smoothened (Smo) STAT TNIK Wnt/beta/catenin

FLT3 Ack1 (TNK2) Angiopoietin Receptor Bcr-Abl BMX Kinase Breast Tumor Kinase BTK c-Fes Kinase c-RET CSF1R DDR Ephrin Receptor FAK Insulin Receptor Src TAM Receptor Tie-2 Trk Receptor

TGFBR

Proteasome Caspase Cysteine Protease DUB E1 E2 E3 Ubiquitin Ligase Endogenous Metabolite HSP NEDD8 Other Targets p97 Serine Protease Tyrosinase

E3 Ligase Ligand PEGn PROTAC

PDK Akt S6 Kinase GSK-3 MELK mTOR PI3K PI4K PIKfyve

14-3-3 Protein AAK1 Amyloids Antioxidant BMI-1 ChoK Clathrin DGK Fluorescent Dye Glutathione Reductase GRK (GPCRK) mPTP Other Targets PCSK9 Platelet aggregation PTEN SMN2 Spliceosome Thrombin TSPO VD

c-Fos/AP-1 CREB/CBP eIF Foxo1 GATA Binding Protein Keap1-Nrf2 KLF LXR MLR PGC-1α Progesterone Receptor RAR/RXR ROR

MALT1 TAK1 NOD Free radical scavengers

Norepinephrine P2 Receptor Adiponectin Receptor Other Targets Gamma-secretase GluR GlyT inhibitor

Flavonoids Terpenoids Phenols

HCV Antibiotic ribosome Antifection Antifungal Arenavirus CMV Enterovirus Filovirus Fungal GluCls HBV HIV HPV HSV Influenza Virus Other Targets Parasite Reverse Transcriptase Rhinovirus

CYPs 11β-HSD 15-PGDH ACC ACE AChE Adenylate Cyclase ALDH Aldose Reductase Aminopeptidase Transferase BACE Casein Kinase CAT Cathepsin CETP COMT CPG2 Decarboxylase Dehydrogenase DGAT Dopamine beta-hydroxylase DPP Elastase FAAH TPH Factor Xa Fatty Acid Synthase Ftase FXR Glucokinase GSNOR Guanylate Cyclase HMGCR IDH IDO Xanthine Oxidase (XAO) IMPDH LDH Steroid Sulfatase (STS) Lipase Lipid Lipoxygenase MAGL SCD MAO Retinoid Receptor MMP NAMPT Neprilysin NKCC Other Targets P450 PAI-1 Vitamin Phosphatase Renin Phospholipase PPAR Protein Phosphatase/PTP Thioredoxin LDL

GlyT AMPK ASBT Transporter BCRP Beta Amyloid Carbonic Anhydrase Chloride Channel CRAC Channel CRM1 Exportin-1 FABP GAT GLUT Glutamate Transporter HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter MTP nAChR NADPH Na-K-ATPase NKCC NMDAR OCT Other Targets P2X Receptor P-glycoprotein Proton Pump Sodium Channel TRP/TRPV Channel URAT1

MEK p38 MAPK Ras Raf ERK JNK MAPKAPK2 (MK2) MAP4K MNK MLK Other Targets

STAT Pim

PGE synthase Amino Acids and Derivatives Antiviral CD110 Cell wall Complement System FLAP Hydroxylase Interferon Receptor IRAK IκB kinase (IKK) Lipoxygenase LTR MyD88 NOS PD-1/PD-L1 RLR ROS Scavenger Receptor SphK STING TLR

Urotensin Receptor ACAT Angiotensin Receptor Antibacterial Bombesin Receptor Vasopressin Receptor Bradykinin Receptor Calcium Channel cAMP Cannabinoid Receptor CaSR CGRP Receptor Chemokine Receptor Cholecystokinin Receptor CRF Receptor Dopamine Receptor Endothelin Receptor FFAR Galanin Receptor GHSR Glucagon Receptor GPCR19 GPR119 Hedgehog (Hh) Histamine Receptor Imidazoline Receptor Leukotriene Receptor LHR LPA Receptor Somatostatin Receptor Lysophospholipid Receptor mAChR MCHR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Orexin Receptor Other Targets OXTR P2Y Receptor PAR Platelet-activating Factor Receptor Prostaglandin Receptor PTH Receptor S1P Receptor SGLT

GPR MRP GR Aromatase Opioid Receptor Estrogen Receptor/ERR CaMK Androgen Receptor (AR) RAAS THR COX Reductase Adrenergic Receptor 5-HT Receptor ATPase Annexin A AhR AChR

Akt Microtubule/Tubulin Myosin Selectin Kinesin Dynamin Dynein Galectin Cadherin HSP Ezrin Arp2/3 complex Glucokinase Arginase GST Gap Junction Protein

Sirtuin HMTase DNMT Histone Demethylase HAT Epigenetic Reader Domain Bromodomain MicroRNA CRISPR/Cas9 COX

ABC AChR Antifolate ATM/ATR Aurora Kinase CLK c-Myc DHFR DNA Alkylator DNA gyrase DNA Repair Protein DNA/RNA Synthesis DNA-PK GPR HDAC Hec1/Nek2 Integrin LIM Kinase (LIMK) Mps1/TTK Nucleoside Antimetabolite/Analog Other Targets PARP PLK Potassium Channel RAD51 Rho ROCK Telomerase Topoisomerase Wee1

Mitophagy Atg Autophagy ULK LRRK2 SIK WNK Kinase Sigma receptor Other Targets Arginase CXCR Thrombin CCR

IAP MDM2-p53 PKA Fas Receptor DAPK IL Receptor Apoptosis Caspase Other Targets Ferroptosis PKD RIP kinase PERK Serine/threonin kinase TNF Apaf-1 Adenosine Receptor CFTR NF-κB p53

ADC Cytotoxin ADCs Linker/Click Chemistry Drug-Linker Conjugates

ALK EGFR FAK IGF-1R FGFR Bcr-Abl Chk JAK Bcl-2 VDA PDGFR c-Met/HGFR FLT VEGFR PDE HIF/HIF Prolyl-hydroxylase CDK c-Kit Other Targets Src PKC Adrenergic Receptor Syk HER/HSP