Enterovirus
Enterovirus is a genus of ubiquitous small (with capsids 1530 nm in diameter) RNAcontaining viruses. These viruses infect higher vertebrates and cause a wide spectrum of diseases. These diseases may appear as short duration sickness or may cause incurable damage in an infected organism, central nervous system diseases, paralysis, swelling, and even death. They are also a cause of other severe deadly diseases such as aseptic meningitis, enteroviral encephalitis, and enteroviral vesicular stomatitis. At the same time, the common cold is also caused by viruses belonging to this genus. Enteroviruses are readily transmitted from person to person through an air and/or via a fecaloral route. Genus Enterovirus belonging to family Picornaviridae includes nine enterovirus species (namely, Enterovirus A, B, C, D, E, F, G, H, and J) and three rhinovirus species (Rhinovirus A, B, and C).
References
1.Nikonov OS, et al. Biochemistry (Mosc). 2017;82(13):1615–1631.
References
1.Nikonov OS, et al. Biochemistry (Mosc). 2017;82(13):1615–1631.
Microbiology/Virology
Enterovirus
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Norwogonin
catalog no : M21505
cas no: 4443-09-8
Norwogonin isolated from Scutellaria baicalensis Georgi possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml). -
TTP-8307
catalog no : M16795
cas no: 950225-08-8
TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses. -
T-00127-HEV1
catalog no : M16477
cas no: 900874-91-1
T-00127-HEV1 is a broad-spectrum antienterovirus compound that selectively inhibits PI4KB activity with IC50 of 60 nM. -
ICA135
catalog no : M16064
cas no: 825601-94-3
ICA135 (ICA-135, ICA 135) is a broad-spectrum inhibitor against human enteroviruses that inhibits Coxsackievirus A10 (CV-A10) replication in RD cells with IC50 of 1.446 uM. -
Enviroxime
catalog no : M15766
cas no: 72301-79-2
Enviroxime (Zinviroxime;NSC346230;LY-122772) is a benzimidazole derivative with antiviral activity against Rhinoviruses and Enteroviruses.