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Epigenetic Reader Domain
Chromatin/Epigenetic
Epigenetic Reader Domain
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GSK778 hydrochloride
catalog no : M37654
cas no: 2863657-79-6
GSK778 hydrochloride hydrochloride is a potent and selective BD1 bromodomain inhibitor of the BET proteins, with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively.
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DW71177
catalog no : M37566
cas no: 2241311-72-6
DW71177 is a bd1-selective and potent BET inhibitor with potent anti-leukemic activity for the study of leukemia.
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BRD4?Inhibitor-27
catalog no : M37196
cas no: 930039-92-2
BRD4?Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 μM, respectively.BRD4?Inhibitor-27 has anticancer activity and can be used for breast cancer research.
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Tz-Thalidomide
catalog no : M37130
cas no: 2087490-42-2
Tz-Thalidomide is a tetrazine-modified Thalidomide (E3 ligase ligand) with some affinity for BRD4.
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BRD4-IN-4
catalog no : M36855
cas no: 304685-40-3
BRD4-IN-4 is a selective BRD4 inhibitor with an IC50 value of 6.83 μM for BRD4.BRD4-IN-4 selectively inhibits the proliferation of the MV4-11 cell line and arrests the cells in G1 phase.BRD4-IN-4 can be used to study MLL leukemias.