Cart
sales@molnova.com
E1
Proteasome/Ubiquitin
E1
-
M435-1279
catalog no : M37630
cas no: 1359431-16-5
M435-1279 is a UBE2T inhibitor that blocks UBE2T-mediated degradation of RACK1, thereby inhibiting the hyperactivation of the Wnt/β-catenin signaling pathway.
-
UC-764864
catalog no : M37227
cas no: 278806-03-4
UC-764864 is a selective UBE2N inhibitor that blocks E1-UBE2N thioester transfer, inhibits innate immune signaling and induces cytotoxic effects in MDS/AML cell lines and primary cells. In addition, UC-764864 reduces the ubiquitination status of UBE2N and can be used to study leukemia.
-
Cbl-b-IN-3
catalog no : M35743
cas no: 2573775-59-2
Cbl-b-IN-3 is a potent inhibitor of casitas b lineage lymphoma proto-oncogene-b (Cbl-b) (ic50 < 1 nM).
-
TAS4464 hydrochloride
catalog no : M26476
cas no: 1848959-11-4
TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).
-
NSC232003
catalog no : M26342
cas no: 1905453-18-0
NSC232003 is a highly potent and cell-permeable inhibitor of UHRF1.