MDM2-p53
Apoptosis
MDM2-p53
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p53-MDM2-IN-1
catalog no : M36397
cas no: 381717-91-5
p53-MDM2-IN-1 (Example 30), an inhibitor of the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 μM and holds potential for applications in anti-tumor research. -
Brigimadlin
catalog no : M36316
cas no: 2095116-40-6
Brigimadlin (BI 907828) is an orally active and highly potent E3 ubiquitin-protein ligase -
p53-Mdm2 inhibitor 4
catalog no : M35928
cas no: 350678-63-6
p53-Mdm2 inhibitor 4 inhibits the p53-MDM2 protein-protein interaction. -
Amifostine thiol
catalog no : M34956
cas no: 31098-42-7
Amifostine thiol (WR-1065) is a radioprotectant that protects DNA from fast neutron-induced strand breaks. -
RO-5963
catalog no : M33481
cas no: 1416663-77-8
RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).