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Norwogonin

CAS No. 4443-09-8

Norwogonin( 578-Trihydroxyflavone )

Catalog No. M21505 CAS No. 4443-09-8

Norwogonin isolated from Scutellaria baicalensis Georgi possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Norwogonin
  • Note
    Research use only, not for human use.
  • Brief Description
    Norwogonin isolated from Scutellaria baicalensis Georgi possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).
  • Description
    Norwogonin isolated from Scutellaria baicalensis Georgi possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).
  • In Vitro
    Norwogonin (0.4, 2, 10, and 50 μg/mL; 48 hours) inhibits EV71 replication in Vero cells and prevents the cytotoxicity induced by EV71 infection. Norwogonin (50 μg/mL; 48 hours) dramatically decreases viral VP2 protein expression.Norwogonin (50 μg/mL; 48 hours) strongly decreases the expression of EV71 NCR gene at 48 h.
  • In Vivo
    ——
  • Synonyms
    578-Trihydroxyflavone
  • Pathway
    Microbiology/Virology
  • Target
    Enterovirus
  • Recptor
    EV71
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4443-09-8
  • Formula Weight
    270.24
  • Molecular Formula
    C15H10O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:20mg/ml(74.01mM)
  • SMILES
    Oc(c1c2OC(c3ccccc3)=CC1=O)cc(O)c2O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Choi HJ et al. Inhibitory Effects of Norwogonin Oroxylin A and Mosloflavone on Enterovirus 71. Biomol Ther (Seoul). 2016 Sep 1;24(5):552-8.
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  • Norwogonin

    Norwogonin isolated from Scutellaria baicalensis Georgi possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).

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