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Propofol

CAS No. 2078-54-8

Propofol ( Propofol; 2,6-DIISOPROPYLPHENOL; Diprivan; Disoprofol; Disoprivan )

Catalog No. M13232 CAS No. 2078-54-8

A widely used general anesthetic to induce and maintain anesthesia; influences ligand-gated channels.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Propofol
  • Note
    Research use only, not for human use.
  • Brief Description
    A widely used general anesthetic to induce and maintain anesthesia; influences ligand-gated channels.
  • Description
    A widely used general anesthetic to induce and maintain anesthesia; influences ligand-gated channels, including the GABAA receptor and others; also inhibits conventional kinesin-1 KIF5B and kinesin-2 KIF3AB and KIF3AC, causing a significant reduction in the distances that these processive kinesins can travel without an effect on velocity (EC50<100 nM).
  • Synonyms
    Propofol; 2,6-DIISOPROPYLPHENOL; Diprivan; Disoprofol; Disoprivan
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Kinesin
  • Recptor
    GABAR;SodiumChannel
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    2078-54-8
  • Formula Weight
    178.27
  • Molecular Formula
    C12H18O
  • Purity
    >98% (HPLC)
  • Solubility
    Water: Soluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    CC(C)C1=C(C(=CC=C1)C(C)C)O
  • Chemical Name
    Phenol, 2,6-diisopropyl- (6CI,8CI)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bensel BM, et al. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4281-E4287.
2. Jin WZ, et al. Eur J Pharmacol. 2016 Oct 5;788:37-44.
3. Eaton MM, et al. Curr Neuropharmacol. 2016;14(7):772-80.
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