MAC1

CAS No. 325970-42-1

MAC1 ( Monastrol Antagonizing Compound 1 )

Catalog No. M14057 CAS No. 325970-42-1

MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MAC1
  • Note
    Research use only, not for human use.
  • Brief Description
    MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
  • Description
    MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity; induces the formation of additional microtubule nucleation centers, which allows kinesin Kif15-dependent bipolar spindle assembly in the absence of Eg5 activity.
  • Synonyms
    Monastrol Antagonizing Compound 1
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Kinesin
  • Recptor
    Kinesin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    325970-42-1
  • Formula Weight
    247.34
  • Molecular Formula
    C15H21NO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (E)-1-(1-hydroxycyclohexyl)-3-phenylpropan-1-one oxime

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Al-Obaidi N, et al. ACS Chem Biol. 2016 Jun 17;11(6):1544-51.
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