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MAC1

CAS No. 325970-42-1

MAC1( Monastrol Antagonizing Compound 1 )

Catalog No. M14057 CAS No. 325970-42-1

MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

MAC1
Note

Research use only, not for human use.
Brief Description

MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
Description

MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity; induces the formation of additional microtubule nucleation centers, which allows kinesin Kif15-dependent bipolar spindle assembly in the absence of Eg5 activity.
In Vitro

——
In Vivo

——
Synonyms

Monastrol Antagonizing Compound 1
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Kinesin
Recptor

Kinesin
Research Area

——
Indication

——

Chemical Information

CAS Number

325970-42-1
Formula Weight

247.338
Molecular Formula

C15H21NO2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

(E)-1-(1-hydroxycyclohexyl)-3-phenylpropan-1-one oxime

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Al-Obaidi N, et al. ACS Chem Biol. 2016 Jun 17;11(6):1544-51.

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