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Varlitinib
CAS No. 845272-21-1
Varlitinib ( ASLAN001;ARRY-334543 )
Catalog No. M19459 CAS No. 845272-21-1
Varlitinib is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM respectively. Phase 2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 60 | Get Quote |
|
| 5MG | 87 | Get Quote |
|
| 10MG | 155 | Get Quote |
|
| 25MG | 259 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameVarlitinib
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NoteResearch use only not for human use.
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Brief DescriptionVarlitinib is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM respectively. Phase 2.
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DescriptionVarlitinib is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM respectively. Phase 2.
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SynonymsASLAN001;ARRY-334543
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR/ErbB1; HER2/ErbB2
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Research AreaCancer
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IndicationBiliary Cancer
Chemical Information
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CAS Number845272-21-1
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Formula Weight466.94
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Molecular FormulaC22H19ClN6O2S
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Purity>98% (HPLC)
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SolubilityDMSO:6 mg/mL (12.84 mM);Ethanol:<1 mg/mL;Water:<1 mg/mL
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SMILESC[C@@H]1COC(NC2=CC3=C(C=C2)N=CN=C3NC2=CC(Cl)=C(OCC3=NC=CS3)C=C2)=N1
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Chemical Name(R)-N4-(3-chloro-4-(thiazol-2-ylmethoxy)phenyl)-N6-(4-methyl-45-dihydrooxazol-2-yl)quinazoline-46-diamine.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Miknis G et al. Abstracts #3399.
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