5-Iodotubercidin

CAS No. 24386-93-4

5-Iodotubercidin ( NSC 113939; 5-ITu )

Catalog No. M17451 CAS No. 24386-93-4

5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 47 In Stock
5MG 84 In Stock
10MG 141 In Stock
25MG 324 In Stock
50MG 482 In Stock
100MG 696 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    5-Iodotubercidin
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.
  • Description
    5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.
  • Synonyms
    NSC 113939; 5-ITu
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    adenosine kinase
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    24386-93-4
  • Formula Weight
    392.15
  • Molecular Formula
    C11H13IN4O4
  • Purity
    98%
  • Solubility
    DMSO : ≥ 49 mg/mL; 124.95 mM
  • SMILES
    Nc1ncnc2c1c(I)cn2[C@@H]1O[C@H](CO)[C@H](O)C1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang X,etal.Identification of 5-Iodotubercidin as a genotoxic drug with anti-cancer potential. PLoS One. 2013 May 7;8(5):e62527.
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