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Trifluridine

CAS No. 70-00-8

Trifluridine ( NSC 75520; NSC 529182; TFT; Trifluridine )

Catalog No. M15687 CAS No. 70-00-8

Trifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 41 In Stock
50MG 59 In Stock
100MG 78 In Stock
200MG 122 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Trifluridine
  • Note
    Research use only, not for human use.
  • Brief Description
    Trifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase.
  • Description
    Trifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase. TFT also inhibits thymidylate synthase (TS), a rate-limiting enzyme of DNA biosynthesis, and is incorporated into DNA.
  • Synonyms
    NSC 75520; NSC 529182; TFT; Trifluridine
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis; Thymidylate synthase
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    70-00-8
  • Formula Weight
    296.20
  • Molecular Formula
    C10H11F3N2O5
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 59 mg/mL (199.18 mM); Water: 59 mg/mL (199.18 mM); DMSO: 59 mg/mL (199.18 mM)
  • SMILES
    O=C1NC(C(C(F)(F)F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2)=O
  • Chemical Name
    1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione.

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shintani M, et al. Oncol Rep. 2010 May; 23(5):1345-50.
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