N-Nitrosodiethylamine

CAS No. 55-18-5

N-Nitrosodiethylamine ( —— )

Catalog No. M28040 CAS No. 55-18-5

N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-Nitrosodiethylamine
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication.
  • Description
    N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the liver, nasal cavity, trachea, lung and esophagus.(In Vivo):Mice with N-Nitrosodiethylamine (25mg/kg) intraperitonially resulted in fatty liver disease leading to progress of cancer disease.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    55-18-5
  • Formula Weight
    102.1
  • Molecular Formula
    C4H10N2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCN(CC)N=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Aravind AP, Asha KR, Rameshkumar KB. Phytochemical analysis and antioxidant potential of the leaves of Garcinia travancorica Bedd. Nat Prod Res. 2016;30(2):232-6.
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