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SW-044248
CAS No. 522650-83-5
SW-044248( SW 044248;SW044248 )
Catalog No. M14846 CAS No. 522650-83-5
SW-044248 is a novel selective inhibitor of Topoisomerase I; inhibits Top I differently from camptothecin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100mg | 1596 | In stock |
|
| 50mg | 1140 | In stock |
|
| 10mg | 380 | In stock |
|
Biological Information
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Product NameSW-044248
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NoteResearch use only, not for human use.
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Brief DescriptionSW-044248 is a novel selective inhibitor of Topoisomerase I; inhibits Top I differently from camptothecin.
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DescriptionSW-044248 is a novel selective inhibitor of Topoisomerase I; inhibits Top I differently from camptothecin; selectively toxic for some NSCLC cell lines.Lung Cancer Preclinical
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SynonymsSW 044248;SW044248
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopoI
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Research AreaCancer
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IndicationLung Cancer
Chemical Information
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CAS Number522650-83-5
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Formula Weight421.52
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Molecular FormulaC22H23N5O2S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 30 mg/mL
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SMILESCCN1C2=CC=CC=C2C3=C1N=C(N=N3)SC(C(NC4=CC=CC=C4OC)=O)CC
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Chemical NameButanamide, 2-[(5-ethyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]-N-(2-methoxyphenyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zubovych IO, et al. Mol Cancer Ther. 2016 Jan;15(1):23-36.
2. Kim HS, et al. Cell. 2013 Oct 24;155(3):552-66.
2. Kim HS, et al. Cell. 2013 Oct 24;155(3):552-66.
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