SB-756050

CAS No. 447410-57-3

SB-756050 ( SB-756050; SB 756050; SB756050 )

Catalog No. M17511 CAS No. 447410-57-3

SB756050 is a specific TGR5 agonist.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 32 In Stock
10MG 53 In Stock
25MG 98 In Stock
50MG 160 In Stock
100MG 259 In Stock
500MG 617 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SB-756050
  • Note
    Research use only, not for human use.
  • Brief Description
    SB756050 is a specific TGR5 agonist.
  • Description
    SB-756050 is a G protein-coupled bile acid receptor 1 (GPBAR1) agonist potentially for the treatment of type 2 diabetes.
  • Synonyms
    SB-756050; SB 756050; SB756050
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    TGR5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    447410-57-3
  • Formula Weight
    500.59
  • Molecular Formula
    C21H28N2O8S2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 150 mg/mL; 299.65 mM
  • SMILES
    O=S(=O)(N1CCN(S(=O)(=O)c2ccc(OC)c(OC)c2)CCC1)c1ccc(OC)c(OC)c1
  • Chemical Name
    1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hodge RJ, et al. Safety, Pharmacokinetics, and Pharmacodynamic Effects of a Selective TGR5 Agonist, SB-756050, in Type 2 Diabetes. Clin Pharmacol Drug Dev. 2013 Jul;2(3):213-22.
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