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T2AA
CAS No. 1380782-27-3
T2AA ( 4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol; ZINC95605533 )
Catalog No. M28054 CAS No. 1380782-27-3
T2AA is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | Get Quote |
|
| 10MG | 129 | Get Quote |
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| 25MG | 267 | Get Quote |
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| 50MG | 439 | Get Quote |
|
| 100MG | 642 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameT2AA
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NoteResearch use only, not for human use.
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Brief DescriptionT2AA is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction.
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DescriptionT2AA is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction. T2AA suppresses cancer cell growth and causes DNA replication stress by stalling DNA replication forks and inhibiting PCNA interaction with DNA polymerase δ.
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Synonyms4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol; ZINC95605533
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorAntifungal;Coagulation factor
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Research Area——
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Indication——
Chemical Information
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CAS Number1380782-27-3
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Formula Weight511.1
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Molecular FormulaC15H15I2NO3
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Purity>98% (HPLC)
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Solubility——
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SMILESO(C1=C(I)C=C(C[C@@H](CO)N)C=C1I)C2=CC=C(O)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kumar N, et al. Isolation and antifungal properties of cyclo(D-Tyr-L-Leu) diketopiperazine isolated from Bacillus sp. associated with rhabditid entomopathogenic nematode. Natural Product Research 2013, 27(23):2168-217
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