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Home - Products - JAK/STAT Signaling - STAT - S3I-201

S3I-201

CAS No. 501919-59-1

S3I-201 ( NSC 74859 )

Catalog No. M14691 CAS No. 501919-59-1

S3I-201 shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 88 In Stock
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Biological Information

  • Product Name
    S3I-201
  • Note
    Research use only, not for human use.
  • Brief Description
    S3I-201 shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5.
  • Description
    S3I-201 shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5.
  • Synonyms
    NSC 74859
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT3
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    501919-59-1
  • Formula Weight
    365.36
  • Molecular Formula
    C16H15NO7S
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 73 mg/mL (199.8 mM)
  • SMILES
    O=C(O)C1=CC=C(NC(COS(=O)(C2=CC=C(C)C=C2)=O)=O)C=C1O
  • Chemical Name
    2-hydroxy-4-(2-(tosyloxy)acetamido)benzoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Siddiquee K, et al. Proc Natl Acad Sci U S A, 2007, 104(18), 7391-7396.
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