Cart
sales@molnova.com
Home - Products - JAK/STAT Signaling - STAT - Stafib-2

Stafib-2

CAS No. 2097938-74-2

Stafib-2( Stafib 2 )

Catalog No. M13314 CAS No. 2097938-74-2

Stafib-2 (Stafib 2)?is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 596 Get Quote
10MG 848 Get Quote
25MG 1251 Get Quote
50MG 1692 Get Quote
100MG 2304 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Stafib-2
  • Note
    Research use only, not for human use.
  • Brief Description
    Stafib-2 (Stafib 2)?is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.
  • Description
    Stafib-2 (Stafib 2)?is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.
  • In Vitro
    Stafib-2 has an extremely high affinity for STAT5b (Ki=8.8 nM).Stafib-2 (3-10 μM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells.
  • In Vivo
    ——
  • Synonyms
    Stafib 2
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2097938-74-2
  • Formula Weight
    644.466
  • Molecular Formula
    C28H26N2O12P2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (77.58 mM)
  • SMILES
    ——
  • Chemical Name
    4-((2-(4-((4-phenoxyphenyl)carbamoyl)phenoxy)acetamido)methyl)-1,2-phenylene bis(dihydrogen phosphate)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Elumalai N, et al. Sci Rep. 2017 Apr 11;7(1):819.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • AS1517499

    A novel potent STAT6 inhibitor with IC50 of 21 nM in STAT6-dependent promoter reporter assay.

  • Hispidol

    Hispidol ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.

  • IQDMA

    A cell-permeable, small molecule inhibitor of the transcription factor STAT5.

Sign In Join Free