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S-Trityl-L-cysteine
CAS No. 2799-07-7
S-Trityl-L-cysteine ( NSC 83265 )
Catalog No. M13853 CAS No. 2799-07-7
S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 35 | Get Quote |
|
| 100MG | 50 | Get Quote |
|
| 200MG | 72 | Get Quote |
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| 500MG | 120 | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameS-Trityl-L-cysteine
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NoteResearch use only, not for human use.
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Brief DescriptionS-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM).
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DescriptionS-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM); induces mitotic arrest in HeLa cells with an IC50 of 700 nM, and displays antitumor activity.
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SynonymsNSC 83265
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetKinesin
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RecptorKinesin
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Research Area——
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Indication——
Chemical Information
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CAS Number2799-07-7
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Formula Weight363.47
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Molecular FormulaC22H21NO2S
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Purity>98% (HPLC)
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Solubility——
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SMILESC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)SCC(C(=O)O)N
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Chemical NameS-(Triphenylmethyl)-L-cysteine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brier S, et al. Biochemistry. 2004 Oct 19;43(41):13072-82.
2. DeBonis S, et al. Mol Cancer Ther. 2004 Sep;3(9):1079-90.
3. Zhao J, et al. Am J Cancer Res. 2014 Jan 15;4(1):42-52.
2. DeBonis S, et al. Mol Cancer Ther. 2004 Sep;3(9):1079-90.
3. Zhao J, et al. Am J Cancer Res. 2014 Jan 15;4(1):42-52.
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S-Trityl-L-cysteine
S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM).
