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Rbin-1
CAS No. 328023-11-6
Rbin-1( Ribozinoindole-1 )
Catalog No. M20815 CAS No. 328023-11-6
Rbin-1 is a potentspecific inhibitor of eukaryotic ribosome biogenesis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 58 | In Stock |
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| 10MG | 87 | In Stock |
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| 25MG | 205 | In Stock |
|
| 50MG | 356 | In Stock |
|
| 100MG | 530 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRbin-1
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NoteResearch use only, not for human use.
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Brief DescriptionRbin-1 is a potentspecific inhibitor of eukaryotic ribosome biogenesis.
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DescriptionRbin-1 is a potentspecific inhibitor of eukaryotic ribosome biogenesis.
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In VitroRbin-1 is a potent and reversible triazinoindole-based inhibitors of eukaryotic ribosome biogenesis. Rbin-1 inhibits recombinant full-length Mdn1’s ATPase activity. Two of the active analogs (Rbin-1 and Rbin-2) inhibit the ATPase activity by 40% at 1 uM. In particular, an analog (Rbin-2) with a bromine substituent at postion-7 is 10-fold more active than Rbin-1 (GI50=14±1 nM (Rbin-2); 136±7 nM (Rbin-1), n=4, mean±SD).
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In Vivo——
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SynonymsRibozinoindole-1
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PathwayEndocrinology/Hormones
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TargetATPase
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RecptorATPase
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Research Area——
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Indication——
Chemical Information
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CAS Number328023-11-6
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Formula Weight256.33
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Molecular FormulaC13H12N4S
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Purity>98% (HPLC)
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SolubilityDMSO:31 mg/mL (120.94 mM)
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SMILESC=C(C)CSc1nnc2c(n1)[nH]c1ccccc12
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Chemical Name3-((2-Methylallyl)thio)-5H-[124]triazino[56-b]indole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Structural Insights into Mdn1 an Essential AAA Protein Required for Ribosome Biogenesis.
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