Deslanoside( Deacetyllanatoside C | Desacetyllanatoside C )

Catalog No. M21488 CAS No. 17598-65-1

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Product Name

Deslanoside
Note

Research use only, not for human use.
Brief Description

Deslanoside is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane pump resulting in an increase in intracellular sodium and calcium concentrations.
Description

Deslanoside is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane pump resulting in an increase in intracellular sodium and calcium concentrations.
In Vitro

——
In Vivo

——
Synonyms

Deacetyllanatoside C | Desacetyllanatoside C
Pathway

Endocrinology/Hormones
Target

ATPase
Recptor

Na+/K+-ATPase
Research Area

Cardiovascular Disease
Indication

Congestive cardiac insufficiency arrhythmias and heart failure.

CAS Number

17598-65-1
Formula Weight

943.1
Molecular Formula

C47H74O19
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (106.04 mM)
SMILES

C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2CC[C@]3([C@@H](C2)CC[C@@H]4[C@@H]3C[C@H]([C@]5([C@@]4(CC[C@@H]5C6=CC(=O)OC6)O)C)O)C)O)O[C@H]7C[C@@H]([C@@H]([C@H](O7)C)O[C@H]8C[C@@H]([C@@H]([C@H](O8)C)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O)O
Chemical Name

4-((3S5R8R9S10S12R13S14S17R)-1214-dihydroxy-3-(((2R4S5S6R)-4-hydroxy-5-(((2S4S5S6R)-4-hydroxy-5-(((2S4S5S6R)-4-hydroxy-6-methyl-5-(((2S3R4S5S6R)-345-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1013-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one

1.Hauptman PJ et al. Digitalis. Circulation. 1999 Mar 9;99(9):1265-70.

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