Garcinia lactone

CAS No. 27750-13-6

Garcinia lactone( (-)-Hydroxycitric acid lactone )

Catalog No. M24189 CAS No. 27750-13-6

Garcinia lactone is an anti-obesity agent.Garcinia lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 117 In Stock
2MG 88 In Stock
5MG 147 In Stock
10MG 235 In Stock
25MG 397 In Stock
50MG 554 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Garcinia lactone
  • Note
    Research use only, not for human use.
  • Brief Description
    Garcinia lactone is an anti-obesity agent.Garcinia lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.
  • Description
    Garcinia lactone is an anti-obesity agent.Garcinia lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.
  • In Vitro
    ——
  • In Vivo
    (-)-Hydroxycitric acid lactone (1000-3000mg/kg; fed for a period of 4 weeks) significantly decreases body weight at 2000 and 3000 mg/kg in chicken. Animal Model:1-day-old male broiler chickens Dosage:1000, 2000, 3000 mg/kg Administration:Fed for a period of 4 weeksResult:Body weight and average daily gain (ADG) in the 2000 mg/kg and 3000 mg/kg were significantly lower.
  • Synonyms
    (-)-Hydroxycitric acid lactone
  • Pathway
    Endocrinology/Hormones
  • Target
    ATPase
  • Recptor
    ATP citrate lyase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    27750-13-6
  • Formula Weight
    190.11
  • Molecular Formula
    C6H6O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1315.03 mM)
  • SMILES
    O[C@@](C1)([C@@H](C(O)=O)OC1=O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jena BS, et al. Chemistry and biochemistry of (-)-hydroxycitric acid from Garcinia. J Agric Food Chem. 2002 Jan 2;50(1):10-22.
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