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RU-505
CAS No. 1314206-29-5
RU-505( RU505 )
Catalog No. M11262 CAS No. 1314206-29-5
RU-505 is an effective inhibitor of the Aβ42-fibrinogen interaction with IC50 of 2.72 uM in FP assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRU-505
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NoteResearch use only, not for human use.
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Brief DescriptionRU-505 is an effective inhibitor of the Aβ42-fibrinogen interaction with IC50 of 2.72 uM in FP assays.
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DescriptionRU-505 is an effective inhibitor of the Aβ42-fibrinogen interaction with IC50 of 2.72 uM in FP assays; restores Aβ-induced altered fibrin clot formation and degradation in vitro and inhibits vessel occlusion in AD transgenic mice, significantly reduces vascular amyloid deposition and microgliosis in the cortex and improves cognitive impairment in mouse models of AD.
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In Vitro——
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In Vivo——
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SynonymsRU505
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PathwayOthers
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TargetAmyloids
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RecptorAmyloids
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Research Area——
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Indication——
Chemical Information
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CAS Number1314206-29-5
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Formula Weight473.596
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Molecular FormulaC28H32FN5O
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=NC2=CC(C(C)(C)C)=NN2C(C3=CC=C(F)C=C3)=C1)N(CCN(C)C)CC4=CC=CC=C4
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Chemical NameN-[2-(dimethylamino)ethyl]-2-(1,1-dimethylethyl)-7-(4-fluorophenyl)-N-(phenylmethyl)-pyrazolo[1,5-a]pyrimidine-5-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ahn HJ, et al. J Exp Med. 2014 Jun 2;211(6):1049-62.
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