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TH-237A
CAS No. 935467-97-3
TH-237A( TH 237A | TH237A | meso-GS 164 )
Catalog No. M16689 CAS No. 935467-97-3
A novel, brain penetrant neuroprotective agent that protects neurons against β-amyloid (Aβ) induced neurotoxicity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 1176 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameTH-237A
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NoteResearch use only, not for human use.
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Brief DescriptionA novel, brain penetrant neuroprotective agent that protects neurons against β-amyloid (Aβ) induced neurotoxicity.
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DescriptionA novel, brain penetrant neuroprotective agent that protects neurons against β-amyloid (Aβ) induced neurotoxicity; increases neuronal survival in the presence of the Aβ peptides in rat isolated neuronal culture with EC50 of 5 nM.
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In Vitro——
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In Vivo——
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SynonymsTH 237A | TH237A | meso-GS 164
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PathwayOthers
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TargetAmyloids
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RecptorAmyloids
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number935467-97-3
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Formula Weight333.3293
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Molecular FormulaC18H17F2NO3
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 46 mg/mL
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SMILESOC[C@@]12N([C@H](C3=CC=C(F)C=C3)OC2)[C@@H](C4=CC=C(F)C=C4)OC1
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Chemical Name1H,3H,5H-Oxazolo[3,4-c]oxazole-7a(7H)-methanol, 3,5-bis(4-fluorophenyl)-, (3R,5S)-rel-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kelly E. Desino. Improving Blood Brain Barrier Permeation of Small Molecules Exhibiting Chemotherapeutic and Neuroprotective Effects.
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