Phytohemagglutinin

CAS No. 9008-97-3

Phytohemagglutinin( PHA-M )

Catalog No. M22701 CAS No. 9008-97-3

Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 41 In Stock
10MG 61 In Stock
25MG 111 In Stock
50MG 178 In Stock
100MG 286 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Phytohemagglutinin
  • Note
    Research use only, not for human use.
  • Brief Description
    Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
  • Description
    Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
  • In Vitro
    Phytohemagglutinin (PHA-M) binds to the membranes of T-cells, stimulates metabolic activity, cell division, and involves inflammatory pathways.Apoptosis Analysis Cell Line:A20 (mouse B cell lymphoma, TLB-208), BW5147.3 (mouse T cell lymphoma, TIB-47), EL4 (mouse T cell lymphoma, TIB-39) Concentration:20 μg/ml Incubation Time:20-48 hours Result:Enhanced apoptosis in A20, BW5147.3 and EL4 cells.
  • In Vivo
    Phytohemagglutinin (100 μg; i.p.; daily for 2 days) inhibits A20 tumor growth. Animal Model:CB17-SCID Mice (bearing A20 cells)Dosage:100 μg Administration:I.p.; daily for 2 days Result:Inhibited A20 tumor growth.
  • Synonyms
    PHA-M
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    9008-97-3
  • Formula Weight
    ——
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:50 mg/mL (Need ultrasonic);DMSO:< 1 mg/mL (insoluble or slightly soluble)
  • SMILES
    N/A
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Movafagh A, et al. The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure. Iran J Pharm Res. 2011 Fall;10(4):895-903.
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