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Phytohemagglutinin
CAS No. 9008-97-3
Phytohemagglutinin( PHA-M )
Catalog No. M22701 CAS No. 9008-97-3
Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 41 | In Stock |
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| 10MG | 61 | In Stock |
|
| 25MG | 111 | In Stock |
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| 50MG | 178 | In Stock |
|
| 100MG | 286 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePhytohemagglutinin
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NoteResearch use only, not for human use.
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Brief DescriptionPhytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
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DescriptionPhytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
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In VitroPhytohemagglutinin (PHA-M) binds to the membranes of T-cells, stimulates metabolic activity, cell division, and involves inflammatory pathways.Apoptosis Analysis Cell Line:A20 (mouse B cell lymphoma, TLB-208), BW5147.3 (mouse T cell lymphoma, TIB-47), EL4 (mouse T cell lymphoma, TIB-39) Concentration:20 μg/ml Incubation Time:20-48 hours Result:Enhanced apoptosis in A20, BW5147.3 and EL4 cells.
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In VivoPhytohemagglutinin (100 μg; i.p.; daily for 2 days) inhibits A20 tumor growth. Animal Model:CB17-SCID Mice (bearing A20 cells)Dosage:100 μg Administration:I.p.; daily for 2 days Result:Inhibited A20 tumor growth.
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SynonymsPHA-M
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number9008-97-3
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Formula Weight——
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Molecular Formula——
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Purity>98% (HPLC)
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SolubilityH2O:50 mg/mL (Need ultrasonic);DMSO:< 1 mg/mL (insoluble or slightly soluble)
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SMILESN/A
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Movafagh A, et al. The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure. Iran J Pharm Res. 2011 Fall;10(4):895-903.
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