Cart
sales@molnova.com
ZDLD20
CAS No. 2762279-02-5
ZDLD20( —— )
Catalog No. M35585 CAS No. 2762279-02-5
ZDLD20 is an orally active and selective CDK4 inhibitor, a β-carboline analog with anti-HCT116 and anticancer activity that inhibits colony formation, inhibits invasion and migration, induces apoptosis, and prevents the G1 phase of the cell cycle.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 107 | In Stock |
|
| 10MG | 176 | In Stock |
|
| 25MG | 353 | In Stock |
|
| 50MG | 554 | In Stock |
|
| 100MG | 886 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1748 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameZDLD20
-
NoteResearch use only, not for human use.
-
Brief DescriptionZDLD20 is an orally active and selective CDK4 inhibitor, a β-carboline analog with anti-HCT116 and anticancer activity that inhibits colony formation, inhibits invasion and migration, induces apoptosis, and prevents the G1 phase of the cell cycle.
-
DescriptionZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2762279-02-5
-
Formula Weight386.45
-
Molecular FormulaC22H22N6O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NC1=NC=C(C=C1)N2CCN(C)CC2)C3=NC=CC=4C=5C=CC=CC5NC34
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Deping Li, et al. Facile synthesis of C1-substituted β-carbolines as CDK4 inhibitors for the treatment of cancer. Bioorg Chem. 2022 Apr;121:105659.?
molnova catalog
related products
-
LCS3
LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively.
-
3-Methoxy-9H-Carbazo...
3-methoxy-9H-carbazole is a photosensitizer, a natural compound from Klauseneria heptaphylla and Klauseneria indica.3-methoxy-9H-carbazole has anti-breast cancer activity and induces apoptosis.
-
TL02-59
TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively.
