Cart
sales@molnova.com
SLU-PP-1072
CAS No. 2285432-57-5
SLU-PP-1072( —— )
Catalog No. M36943 CAS No. 2285432-57-5
SLU-PP-1072 is an ERRα and ERRγ inverse dual agonist that disrupts PCa cell metabolism and induces apoptosis through cell cycle dysregulation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 116 | In Stock |
|
| 10MG | 187 | In Stock |
|
| 25MG | 377 | In Stock |
|
| 50MG | 548 | In Stock |
|
| 100MG | 784 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1609 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSLU-PP-1072
-
NoteResearch use only, not for human use.
-
Brief DescriptionSLU-PP-1072 is an ERRα and ERRγ inverse dual agonist that disrupts PCa cell metabolism and induces apoptosis through cell cycle dysregulation.
-
DescriptionSLU-PP-1072 is a dual ERRα/γ inverse agonist, used in Prostate cancer (PCa) research. SLU-PP-1072 disrupts PCa cell metabolism, and induces apoptosis via dysregulating cell cycle.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis | Estrogen/progestogen Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2285432-57-5
-
Formula Weight336.36
-
Molecular FormulaC18H12N2O3S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (371.63 mM; Ultrasonic )
-
SMILESC(NC=1C=C2C(=CC1)N=CS2)(=O)C=3OC(=CC3)C4=CC=C(O)C=C4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Schoepke E, et al. A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells. ACS Chem Biol. 2020 Sep 18;15(9):2338-2345.?
molnova catalog
related products
-
KS106
KS106 is a selective and potent ALDH inhibitor with antiproliferative and anticancer activity, inhibits ALDH1A1, ALDH2, and ALDH3A1 with IC50 of 334, 2137, and 360 nM, respectively.
-
SD-36
SD-36 is a selective and efficient STAT3 protein degrader (Kd=~50 nM) with antitumor activity that promotes growth inhibition and induces apoptosis by inhibiting Mcl-1 in gliomas.SD-36 inhibits the transcriptional activity of STAT3.
-
Hinokitiol
Hinokitiol (4-Isopropyltropolone;β-Thujaplicin) is a tropolone-related natural compound that can induces apoptosis and cell cycle arrest.
