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SLU-PP-1072

CAS No. 2285432-57-5

SLU-PP-1072( —— )

Catalog No. M36943 CAS No. 2285432-57-5

SLU-PP-1072 is an ERRα and ERRγ inverse dual agonist that disrupts PCa cell metabolism and induces apoptosis through cell cycle dysregulation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SLU-PP-1072
  • Note
    Research use only, not for human use.
  • Brief Description
    SLU-PP-1072 is an ERRα and ERRγ inverse dual agonist that disrupts PCa cell metabolism and induces apoptosis through cell cycle dysregulation.
  • Description
    SLU-PP-1072 is a dual ERRα/γ inverse agonist, used in Prostate cancer (PCa) research. SLU-PP-1072 disrupts PCa cell metabolism, and induces apoptosis via dysregulating cell cycle.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis | Estrogen/progestogen Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2285432-57-5
  • Formula Weight
    336.36
  • Molecular Formula
    C18H12N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (371.63 mM; Ultrasonic )
  • SMILES
    C(NC=1C=C2C(=CC1)N=CS2)(=O)C=3OC(=CC3)C4=CC=C(O)C=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schoepke E, et al. A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells. ACS Chem Biol. 2020 Sep 18;15(9):2338-2345.?
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