PF-06648671 ( PF6648671 )

Catalog No. M12266 CAS No. 1587727-31-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

PF-06648671
Note

Research use only, not for human use.
Brief Description

PF-06648671 (PF6648671) is a novel oral γ-secretase modulator being developed for the treatment of Alzheimer's disease.
Description

PF-06648671 (PF6648671) is a novel oral γ-secretase modulator being developed for the treatment of Alzheimer's disease.Alzheimer Disease Phase 1 Discontinued
Synonyms

PF6648671
Pathway

Wnt/Notch/Hedgehog
Target

γ-secretase
Recptor

γ-secretase
Research Area

——
Indication

——

CAS Number

1587727-31-8
Formula Weight

538.93
Molecular Formula

C25H23ClF4N4O3
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C1C(N2CCN1[C@H]([C@H]3O[C@@H](C4=CC(F)=C(Cl)C=C4C(F)(F)F)CC3)C)=CC=C(N5C=C(C)N=C5)C2=O
Chemical Name

2H-Pyrido[1,2-a]pyrazine-1,6-dione, 2-[(1S)-1-[(2S,5R)-5-[4-chloro-5-fluoro-2-(trifluoromethyl)phenyl]tetrahydro-2-furanyl]ethyl]-3,4-dihydro-7-(4-methyl-1H-imidazol-1-yl)-