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AN-12-H5
CAS No. 1193340-31-6
AN-12-H5( —— )
Catalog No. M10672 CAS No. 1193340-31-6
AN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1229 | Get Quote |
|
| 50MG | 2507 | Get Quote |
|
| 100MG | 3168 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAN-12-H5
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NoteResearch use only, not for human use.
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Brief DescriptionAN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM.
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DescriptionAN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM; mutations in capsid proteins (G3112A, VP1-Ala224Thr, and G2396A, VP3-Arg227Lys mutations) are resistant to AN-12-H5.
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In VitroAN-12-H5 shows no inhibitory effect on PI4KB activity and only moderate inhibitory effects on PI 3-kinase activity.
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetEnterovirus
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RecptorEnterovirus
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Research Area——
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Indication——
Chemical Information
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CAS Number1193340-31-6
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Formula Weight513.645
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Molecular FormulaC24H23N3O4S3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (194.69 mM)
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SMILES——
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Chemical NameN-((6aS,8S)-2-(4-(methylthio)phenyl)-6,12-dioxo-5,6,6a,7,8,9,10,12-octahydrobenzo[e]pyrido[1,2-a][1,4]diazepin-8-yl)thiophene-2-sulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Arita M, et al. J Gen Virol. 2010 Nov;91(Pt 11):2734-44.
2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72.
3. Arita M, et al. J Virol. 2013 Apr;87(8):4252-60.
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