NSC232003

CAS No. 1905453-18-0

NSC232003( —— )

Catalog No. M26342 CAS No. 1905453-18-0

NSC232003 is a highly potent and cell-permeable inhibitor of UHRF1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NSC232003
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC232003 is a highly potent and cell-permeable inhibitor of UHRF1.
  • Description
    NSC232003 is a highly potent and cell-permeable inhibitor of UHRF1.(In Vitro):NSC232003 is an effective DNA methylation inhibitor and indicate that this particular nucleotide scaffold could provide a versatile basis for the design of potent UHRF1 inhibitors.NSC232003, a uracil derivative freely available by the NCI/DTP repository, provides a versatile lead for developing highly potent and cell-permeable UHRF1 inhibitors that will enable dissection of DNA methylation inheritance.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    E1
  • Recptor
    DP8/9| DPP-4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1905453-18-0
  • Formula Weight
    169.14
  • Molecular Formula
    C6H7N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 2 mg/mL (11.82 mM)
  • SMILES
    C\C(NO)=C1/C=NC(=O)NC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ansorge S, et al. Novel aspects of cellular action of dipeptidyl peptidase IV/CD26. Biol Chem. 2011 Mar;392(3):153-68.
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