2-D08

CAS No. 144707-18-6

2-D08( —— )

Catalog No. M20719 CAS No. 144707-18-6

2-D08 is a synthetic flavone that inhibits sumoylation also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 47 In Stock
10MG 80 In Stock
25MG 170 In Stock
50MG 267 In Stock
100MG 484 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    2-D08
  • Note
    Research use only, not for human use.
  • Brief Description
    2-D08 is a synthetic flavone that inhibits sumoylation also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
  • Description
    2-D08 is a synthetic flavone that inhibits sumoylation also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    E1
  • Recptor
    sumoylation|AXL
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    144707-18-6
  • Formula Weight
    270.24
  • Molecular Formula
    C15H10O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:150 mg/mL (555.06 mM)
  • SMILES
    Oc1ccc(-c2cc(=O)c3ccccc3o2)c(O)c1O
  • Chemical Name
    2-(234-trihydroxyphenyl)-4H-1-benzopyran-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim Y Nagy K Keyser S et al. An Electrophoretic Mobility Shift Assay Identifies a Mechanistically Unique Inhibitor of Protein Sumoylation[J]. Chemistry & Biology 2013 20(4):604-613.
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