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NE-100
CAS No. 149860-29-7
NE-100( NE 100 | NE100 )
Catalog No. M12082 CAS No. 149860-29-7
A potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameNE-100
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM.
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DescriptionA potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM; dispalys 205-fold selectivity over sigma-2, 1,000-fold selectivity over D1, D2, PCP, α1, 5-HT1A and 5-HT2 receptors; shows antipsychotic activity in vivo.Schizophrenia Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsNE 100 | NE100
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PathwayAutophagy
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TargetSigma receptor
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RecptorSigma Receptor
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Research AreaNeurological Disease
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IndicationSchizophrenia
Chemical Information
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CAS Number149860-29-7
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Formula Weight355.51
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Molecular FormulaC23H33NO2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nakazato A, et al. J Med Chem. 1999 Mar 25;42(6):1076-87.
2. Berardi F, et al. Bioorg Med Chem. 2001 May;9(5):1325-35.
3. Ogawa S, et al. Eur J Pharmacol. 1994 Sep 22;263(1-2):9-15.
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