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Sigma-LIGAND-1
CAS No. 139652-01-0
Sigma-LIGAND-1( —— )
Catalog No. M33195 CAS No. 139652-01-0
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with IC50 values of 16 nM and 19 nM at the DTG site and the PPP site, respectively, and a Ki of 4000 nM at the dopamine D2 receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 116 | In Stock |
|
| 5MG | 101 | In Stock |
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| 10MG | 150 | In Stock |
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| 25MG | 235 | In Stock |
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| 50MG | 310 | In Stock |
|
| 100MG | 425 | In Stock |
|
| 200MG | 572 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSigma-LIGAND-1
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NoteResearch use only, not for human use.
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Brief DescriptionSigma-LIGAND-1 is a selective Sigma Receptor ligand with IC50 values of 16 nM and 19 nM at the DTG site and the PPP site, respectively, and a Ki of 4000 nM at the dopamine D2 receptor.
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DescriptionSigma-LIGAND-1 is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor.
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In Vitro——
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In VivoAdministration of Sigma-LIGAND-1 would reverse amphetamine-induced hyperlocomotion in mice, a behavioral model sensitive to antipsychotic compounds. Sigma-LIGAND-1 and its structural analogues have the potential antipsychotic activity.
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Synonyms——
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PathwayAutophagy
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TargetSigma receptor
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RecptorSigma receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number139652-01-0
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Formula Weight435.56
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Molecular FormulaC27H33NO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (229.59 mM; Ultrasonic )
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SMILESCc1c(oc2ccc(OCCCCCCN3CCC(O)CC3)cc2c1=O)-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Erickson RH, et al. (Aminoalkoxy)chromones. Selective sigma receptor ligands. J Med Chem. 1992 May 1;35(9):1526-35.?
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