Ditolylguanidine
CAS No. 97-39-2
Ditolylguanidine( 13-Di-o-tolylguanidine | DTG | Di-o-tolylguanidine )
Catalog No. M20621 CAS No. 97-39-2
Ditolylguanidine is an agonist of sigma receptor (σ1/σ2 receptor).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | 27 | In Stock |
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Biological Information
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Product NameDitolylguanidine
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NoteResearch use only, not for human use.
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Brief DescriptionDitolylguanidine is an agonist of sigma receptor (σ1/σ2 receptor).
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DescriptionDitolylguanidine is an agonist of sigma receptor (σ1/σ2 receptor).
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In Vitro——
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In VivoAnimal Model:Urethane anaesthetized male Std-Wistar rats Dosage:1-5 mg/kg Administration:Intravenous injection; 1-5 mg/kg, once Result:Dose-dependently extended micturition intervals and raised the threshold pressure. Abolished the micturition reflex and urinary dribbling at a dose of 5 mg/kg.
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Synonyms13-Di-o-tolylguanidine | DTG | Di-o-tolylguanidine
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PathwayAutophagy
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TargetSigma receptor
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Recptorσ1/σ2
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Research Area——
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Indication——
Chemical Information
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CAS Number97-39-2
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Formula Weight239.32
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Molecular FormulaC15H17N3
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Purity>98% (HPLC)
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SolubilityDMSO:150 mg/mL (626.78 mM)
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SMILESCc1ccccc1NC(=N)Nc1ccccc1C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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4-PPBP maleate
4-PPBP maleate is a potent σ1 receptor (ligand) agonist and a selective, non-competitive NR1a/2B NMDA receptor antagonist in the context of Xenopus oocytes expression, with neuroprotective properties.
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PRE-084 hydrochlorid...
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
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Glycerol phenylbutyr...
Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Glycerol phenylbutyrate may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders. Glycerol phenylbutyrate also has the potential for the treatment of hyperammonemia.
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