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NBD-14107
CAS No. 2086328-94-9
NBD-14107( NBD14107 )
Catalog No. M13251 CAS No. 2086328-94-9
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameNBD-14107
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NoteResearch use only, not for human use.
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Brief DescriptionA potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
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DescriptionA potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010.HIV Preclinical.
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In Vitro——
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In Vivo——
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SynonymsNBD14107
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number2086328-94-9
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Formula Weight412.84
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Molecular FormulaC17H15ClF2N4O2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-(2-amino-1-(5-(hydroxymethyl)thiazol-2-yl)ethyl)-5-(4-chloro-3,5-difluorophenyl)-1H-pyrrole-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Curreli F, et al. J Med Chem. 2017 Apr 13;60(7):3124-3153.
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