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BMS-707035

CAS No. 729607-74-3

BMS-707035 ( BMS 707035;BMS707035 )

Catalog No. M15791 CAS No. 729607-74-3

BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 50 In Stock
10MG 88 In Stock
25MG 177 In Stock
50MG 324 In Stock
100MG 528 In Stock
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Biological Information

  • Product Name
    BMS-707035
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.
  • Description
    BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.HIV Infection Phase 2 Discontinued
  • Synonyms
    BMS 707035;BMS707035
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV-Iintegrase
  • Research Area
    Infection
  • Indication
    HIV Infection

Chemical Information

  • CAS Number
    729607-74-3
  • Formula Weight
    410.42
  • Molecular Formula
    C17H19FN4O5S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    Cn1c(=O)c(c(nc1N2CCCCS2(=O)=O)C(=O)NCc3ccc(cc3)F)O
  • Chemical Name
    4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dicker IB, et al. J Biol Chem. 2007 Oct 26;282(43):31186-96.
2. Langley DR, et al. Biochemistry. 2008 Dec 23;47(51):13481-8.
3. Al-Mawsawi LQ, et al. Expert Opin Emerg Drugs. 2008 Jun;13(2):213-25.
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