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BMS-707035
CAS No. 729607-74-3
BMS-707035 ( BMS 707035;BMS707035 )
Catalog No. M15791 CAS No. 729607-74-3
BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 50 | In Stock |
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| 10MG | 88 | In Stock |
|
| 25MG | 177 | In Stock |
|
| 50MG | 324 | In Stock |
|
| 100MG | 528 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBMS-707035
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.
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DescriptionBMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.HIV Infection Phase 2 Discontinued
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SynonymsBMS 707035;BMS707035
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV-Iintegrase
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number729607-74-3
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Formula Weight410.42
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Molecular FormulaC17H19FN4O5S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCn1c(=O)c(c(nc1N2CCCCS2(=O)=O)C(=O)NCc3ccc(cc3)F)O
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Chemical Name4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dicker IB, et al. J Biol Chem. 2007 Oct 26;282(43):31186-96.
2. Langley DR, et al. Biochemistry. 2008 Dec 23;47(51):13481-8.
3. Al-Mawsawi LQ, et al. Expert Opin Emerg Drugs. 2008 Jun;13(2):213-25.
2. Langley DR, et al. Biochemistry. 2008 Dec 23;47(51):13481-8.
3. Al-Mawsawi LQ, et al. Expert Opin Emerg Drugs. 2008 Jun;13(2):213-25.
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