NBD-11021
CAS No. 1427304-84-4
NBD-11021 ( NBD11021 )
Catalog No. M11804 CAS No. 1427304-84-4
A small molecule, full antagonist of CD4 that blocks gp120-CD4 interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNBD-11021
-
NoteResearch use only, not for human use.
-
Brief DescriptionA small molecule, full antagonist of CD4 that blocks gp120-CD4 interaction.
-
DescriptionA small molecule, full antagonist of CD4 that blocks gp120-CD4 interaction; inhibits the CD4-dependent virus in a dose-dependent manner with IC50 of 2.4 uM; also weakly shows HIV-1 RT inhibition with IC50 of 43.4 uM; exhibits pan-neutralization activity against a panel of 56 Env-pseudotyped HIV-1 representing diverse subtypes of clinical isolates (IC50 as low as 270 nM).HIV Preclinical
-
SynonymsNBD11021
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1427304-84-4
-
Formula Weight444.98
-
Molecular FormulaC22H25ClN4O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name5-(4-chlorophenyl)-N-((5-(hydroxymethyl)-4-methylthiazol-2-yl)(piperidin-2-yl)methyl)-1H-pyrrole-2-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Curreli F, et al. J Med Chem. 2015 Sep 10;58(17):6909-6927.
molnova catalog
related products
-
Decanoyl-RVKR-CMK
Subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin). Abolishes proET-1 processing in endothelial cells; inhibits regulated secretion of the neuronal polypeptide VGF in PC12 cells.
-
10-Hydroxy-2-decenoi...
10-Hydroxy-2-decenoic acid is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.
-
Vipirinin
A coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages.