N-Acetyl-D-Glucosamine
CAS No. 7512-17-6
N-Acetyl-D-Glucosamine( Acetylglucosamine; GlcNAc; Bio-NAG; GreenNAG )
Catalog No. M19074 CAS No. 7512-17-6
N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
500mg | Get Quote | In Stock |
|
250mg | Get Quote | In Stock |
|
25mg | 45 | In Stock |
|
Biological Information
-
Product NameN-Acetyl-D-Glucosamine
-
NoteResearch use only, not for human use.
-
Brief DescriptionN-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc.
-
DescriptionAcetylglucosamine or N-acetylglucosamine is potentially for the treatment of irritable bowel syndrome. N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc is the monomeric unit of the polymer chitin, the second most abundant carbohydrate after cellulose. In addition to serving as a component of this homogeneous polysaccharide, GlcNAc is also a basic component of hyaluronic acid and keratin sulfate on the cell surface. GlcNAc has been reported to be an inhibitor of elastase release from human polymorphonuclear leukocytes (range 8–17% inhibition), however this is much weaker than the inhibition seen with N-acetylgalactosamine (range 92–100%).
-
SynonymsAcetylglucosamine; GlcNAc; Bio-NAG; GreenNAG
-
PathwayCell Cycle/DNA Damage
-
TargetTopoisomerase
-
RecptorHuman Endogenous Metabolite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number7512-17-6
-
Formula Weight221.21
-
Molecular FormulaC8H15NO6
-
Purity98%
-
Solubility——
-
SMILESOC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O
-
Chemical NameN-Acetyl-beta-D-glucosamine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Liu F,etal.O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10804-9.
molnova catalog
related products
-
Irinotecan
Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.
-
SW-044248
SW-044248 is a novel selective inhibitor of Topoisomerase I; inhibits Top I differently from camptothecin.
-
UAMC 00039 dihydroch...
UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.