N-Acetyl-D-Glucosamine
CAS No. 7512-17-6
N-Acetyl-D-Glucosamine( Acetylglucosamine | GlcNAc | Bio-NAG | GreenNAG )
Catalog No. M19074 CAS No. 7512-17-6
N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 37 | In Stock |
|
| 1G | 43 | In Stock |
|
Biological Information
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Product NameN-Acetyl-D-Glucosamine
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NoteResearch use only, not for human use.
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Brief DescriptionN-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc.
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DescriptionAcetylglucosamine or N-acetylglucosamine is potentially for the treatment of irritable bowel syndrome. N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc is the monomeric unit of the polymer chitin, the second most abundant carbohydrate after cellulose. In addition to serving as a component of this homogeneous polysaccharide, GlcNAc is also a basic component of hyaluronic acid and keratin sulfate on the cell surface. GlcNAc has been reported to be an inhibitor of elastase release from human polymorphonuclear leukocytes (range 8–17% inhibition), however this is much weaker than the inhibition seen with N-acetylgalactosamine (range 92–100%).
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In Vitro——
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In Vivo——
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SynonymsAcetylglucosamine | GlcNAc | Bio-NAG | GreenNAG
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number7512-17-6
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Formula Weight221.21
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Molecular FormulaC8H15NO6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (565.07 mM)
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SMILESOC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O
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Chemical NameN-Acetyl-beta-D-glucosamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liu F,etal.O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10804-9.
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