Cart
sales@molnova.com
Mcl1-IN-2
CAS No. 292057-76-2
Mcl1-IN-2 ( Mcl1-IN-2; Mcl1IN2; Mcl1 IN 2; Mcl1-inhibitor-2; Mcl1 inhibitor 2 )
Catalog No. M13898 CAS No. 292057-76-2
Mcl1-IN-2 is an Mcl-1 inhibitor without a reported IC50 value.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 106 | Get Quote |
|
| 5MG | 178 | Get Quote |
|
| 10MG | 295 | Get Quote |
|
| 25MG | 498 | Get Quote |
|
| 50MG | 716 | Get Quote |
|
| 100MG | 981 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMcl1-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionMcl1-IN-2 is an Mcl-1 inhibitor without a reported IC50 value.
-
DescriptionMcl1-IN-2 is an Mcl-1 inhibitor without a reported IC50 value.
-
SynonymsMcl1-IN-2; Mcl1IN2; Mcl1 IN 2; Mcl1-inhibitor-2; Mcl1 inhibitor 2
-
PathwayAngiogenesis
-
TargetBcl-2
-
RecptorBcl-2
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number292057-76-2
-
Formula Weight333.41
-
Molecular FormulaC19H15N3OS
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESOC(C(N=CC=C1)=C1C=C2)=C2C(C3=CC=CS3)NC4=CC=CC=N4
-
Chemical Name8-Quinolinol, 7-[(2-pyridinylamino)-2-thienylmethyl]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Richard DJ, et al. Bioorg Med Chem. 2013 Nov 1;21(21):6642-9.
2. Zaneta Nikolovska-Coleska, et al. Discovery and characterization of new small-molecule inhibitors of Mcl-1 by high-throughput screening. AACR 2008.
2. Zaneta Nikolovska-Coleska, et al. Discovery and characterization of new small-molecule inhibitors of Mcl-1 by high-throughput screening. AACR 2008.
molnova catalog
related products
-
BT2
BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM.
-
A-1210477
A-1210477 is a potent, selective Mcl-1 inhibitor that bind to Mcl-1 (Ki=0.45 nM) to disrupt MCL-1-BIM complexes.
-
DAN 004
A small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 0.7 uM.
