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MIV-6R
CAS No. 1560968-55-9
MIV-6R( MIV-6R | MIV 6R | MIV6R | VU0516310-1 | VU0516310 1 | VU05163101 )
Catalog No. M12220 CAS No. 1560968-55-9
A potent, ligand-efficient, and cell-active inhibitor menin-MLL interaction with IC50 of 56 nM, Kd of 85 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMIV-6R
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, ligand-efficient, and cell-active inhibitor menin-MLL interaction with IC50 of 56 nM, Kd of 85 nM.
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DescriptionA potent, ligand-efficient, and cell-active inhibitor menin-MLL interaction with IC50 of 56 nM, Kd of 85 nM; demonstrateds strong and selective effects in MLL leukemia cells, and induces more pronounced increase in CD11b expression in MLL-AF9 BMCs.
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In Vitro——
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In Vivo——
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SynonymsMIV-6R | MIV 6R | MIV6R | VU0516310-1 | VU0516310 1 | VU05163101
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorHMTase
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Research Area——
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Indication——
Chemical Information
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CAS Number1560968-55-9
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Formula Weight417.5863
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Molecular FormulaC27H35N3O
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Purity>98% (HPLC)
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Solubility——
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SMILESN#CC1=CC=C(OCCCN2CCC([C@@](C3CCCC3)(N)C4=CC=CC=C4)CC2)C=C1
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Chemical Name(R)-4-(3-(4-(amino(cyclopentyl)(phenyl)methyl)piperidin-1-yl)propoxy)benzonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14.
2. He S, et al. J Med Chem. 2014 Feb 27;57(4):1543-56.
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