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MI-136
CAS No. 1628316-74-4
MI-136 ( MI 136;MI136 )
Catalog No. M12427 CAS No. 1628316-74-4
A potent Menin-MLL interaction inhibitor with IC50 of 31 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 51 | In Stock |
|
| 5MG | 80 | In Stock |
|
| 10MG | 135 | In Stock |
|
| 25MG | 264 | In Stock |
|
| 50MG | 478 | In Stock |
|
| 100MG | 691 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMI-136
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NoteResearch use only, not for human use.
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Brief DescriptionA potent Menin-MLL interaction inhibitor with IC50 of 31 nM.
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DescriptionA potent Menin-MLL interaction inhibitor with IC50 of 31 nM; demonstrates potent inhibitory activity and strong binding affinity to menin.
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SynonymsMI 136;MI136
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorAndrogenReceptor
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1628316-74-4
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Formula Weight470.51
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Molecular FormulaC23H21F3N6S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 31 mg/mL
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SMILESC1CN(CCC1NC2=C3C=C(SC3=NC=N2)CC(F)(F)F)CC4=CC5=C(C=C4)NC(=C5)C#N
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Chemical Name1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Borkin D, et al. J Med Chem. 2016 Feb 11;59(3):892-913.
2. Borkin D, et al. Cancer Cell. 2015 Apr 13;27(4):589-602.
2. Borkin D, et al. Cancer Cell. 2015 Apr 13;27(4):589-602.
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