Cart
sales@molnova.com
icFSP1
CAS No. 1115910-36-5
icFSP1( —— )
Catalog No. M36858 CAS No. 1115910-36-5
icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 631 | In Stock |
|
| 10MG | 884 | In Stock |
|
| 25MG | 1245 | In Stock |
|
| 50MG | 1525 | In Stock |
|
| 100MG | 1855 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameicFSP1
-
NoteResearch use only, not for human use.
-
Brief DescriptionicFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
-
DescriptionicFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1115910-36-5
-
Formula Weight459.49
-
Molecular FormulaC26H25N3O5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (217.63 mM; Ultrasonic )
-
SMILESO=C1N(C(C)=NC=2C1=CC=CC2)C3=CC=C(NC(CC4=CC(OC)=C(OC)C(OC)=C4)=O)C=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Toshitaka Nakamura, et al. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul;619(7969):371-377.?
molnova catalog
related products
-
SF5
SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.
-
Silvestrol aglycone
Silvestrol is a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in cancer cells through the mitochondrial/apoptosome pathway.
-
3-O-Methylgallic aci...
3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
