Oxypalmatine

CAS No. 19716-59-7

Oxypalmatine( —— )

Catalog No. M37729 CAS No. 19716-59-7

Oxypalmatine (8-Oxypalmatine) is a berberine-type alkaloid isolated from Phellodendron amurense that regulates breast cancer cell proliferation and apoptosis by inhibiting PI3K/AKT signaling and its efficacy in breast cancer-like organs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 126 In Stock
10MG 202 In Stock
25MG 339 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Oxypalmatine
  • Note
    Research use only, not for human use.
  • Brief Description
    Oxypalmatine (8-Oxypalmatine) is a berberine-type alkaloid isolated from Phellodendron amurense that regulates breast cancer cell proliferation and apoptosis by inhibiting PI3K/AKT signaling and its efficacy in breast cancer-like organs.
  • Description
    Oxypalmatine is isolated from Phellodendron amurense.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    19716-59-7
  • Formula Weight
    367.4
  • Molecular Formula
    C21H21NO5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 33.33 mg/mL (90.72 mM; Ultrasonic (<60°C)
  • SMILES
    COc1ccc2cc3-c4cc(OC)c(OC)cc4CCn3c(=O)c2c1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Min YD, et al. Isolation of limonoids and alkaloids from Phellodendron amurense and their multidrug resistance (MDR) reversal activity. Arch Pharm Res. 2007;30(1):58-63.?
molnova catalog
related products
  • 3,4,5-Trihydroxycinn...

    3,4,5-Trihydroxycinnamic acid decyl ester, an effective inhibitor of lipid absorption and accumulation, exhibits anti-obesity properties and acts as a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM.

  • Nimbolide

    Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways.

  • Phenoxodiol

    Phenoxodiol activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP) expression, and sensitizes the cancer cells to Fas-mediated apoptosis.