ROCK-IN-5

CAS No. 692870-25-0

ROCK-IN-5( —— )

Catalog No. M35956 CAS No. 692870-25-0

ROCK-IN-5 (compound I-B-37) is a potent inhibitor of protein kinases, including ROCK, ERK, GSK, and AGC, with potential applications in cardiac, proliferative, and neurodegenerative disease research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
10MG 36 In Stock
25MG 60 In Stock
50MG 85 In Stock
100MG 127 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ROCK-IN-5
  • Note
    Research use only, not for human use.
  • Brief Description
    ROCK-IN-5 (compound I-B-37) is a potent inhibitor of protein kinases, including ROCK, ERK, GSK, and AGC, with potential applications in cardiac, proliferative, and neurodegenerative disease research.
  • Description
    ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK, ERK, GSK, and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    ROCK
  • Recptor
    ROCK | ERK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    692870-25-0
  • Formula Weight
    347.79
  • Molecular Formula
    C16H11ClFN3OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC1=C(CC(=O)NC2=NC(=CS2)C2=CC=NC=C2)C(Cl)=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jingrong Cao, et al. Compositions useful as inhibitors of rock and other protein kinases. WO2004041813A1.
molnova catalog
related products
  • Rho-Kinase-IN-1

    Rho-Kinase-IN-1 is a inhibitor of Rho kinase (ROCK) with Ki values of 30.5 and 3.9 nM for ROCK1 and ROCK2, respectively.

  • Chroman 1

    Chroman 1 is a potent inhibitor of ROCK1 (IC50?= 52 pM) and ROCK2 (IC50?= 1 pM).

  • CID-5056270

    CID-5056270 has anticancer activity and can inhibit lung cancer, anal cancer, bladder cancer, cervical cancer, vulvar cancer, penile cancer, Burkitt's lymphoma, breast cancer and bone cancer.