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Home - Products - Proteasome/Ubiquitin - DUB - USP15-IN-1

USP15-IN-1

CAS No. 2260826-16-0

USP15-IN-1( —— )

Catalog No. M35573 CAS No. 2260826-16-0

USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM) with high antiproliferative activity against non-small cell lung cancer and leukemia cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    USP15-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM) with high antiproliferative activity against non-small cell lung cancer and leukemia cells.
  • Description
    USP15-IN-1 is a potent USP15 inhibitor with an IC50 value of 3.76 μM. USP15-IN-1 can be used for researching anticancer.
  • In Vitro
    USP15-IN-1 (compound IM001) (0.001-5 μM; 48 h) exhibits highly anti-proliferative activity against non-small cell lung carcinoma and leukemia cells.Cell Proliferation Assay Cell Line:Non-small cell lung carcinoma and leukemia cells Concentration:0.001 μM, 0.005 μM, 0.01 μM, 0.05 μM, 0.1 μM, 0.5 μM, 1 and 5 μM Incubation Time:48 h Result:Exhibited highly anti-proliferative activity against non-small cell lung carcinoma and leukemia cells with IC50s of 1.94 μM and 2.22 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    DUB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2260826-16-0
  • Formula Weight
    377.44
  • Molecular Formula
    C22H23N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (264.94 mM; Ultrasonic )
  • SMILES
    OCCNC(=O)c1ccc2[nH]c3CN(CCc3c2c1)C(=O)Cc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chen Yihua, et al. The tetrahydro-beta-carboline micromolecular organic compound and its derivative and medical usage of a kind of hydroxyl substitution. CN108727370A
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