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Home - Products - Cell Cycle/DNA Damage - PARP - 5-Hydroxymethyl-2-deoxycytidine

5-Hydroxymethyl-2-deoxycytidine

CAS No. 7226-77-9

5-Hydroxymethyl-2-deoxycytidine( —— )

Catalog No. M35230 CAS No. 7226-77-9

5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 85 In Stock
5MG 76 In Stock
10MG 116 In Stock
25MG 202 In Stock
50MG 315 In Stock
100MG 477 In Stock
200MG Get Quote In Stock
500MG 1014 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    5-Hydroxymethyl-2-deoxycytidine
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.
  • Description
    5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    PARP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    7226-77-9
  • Formula Weight
    257.24
  • Molecular Formula
    C10H15N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (195.11 mM; Ultrasonic )
  • SMILES
    Nc1nc(=O)n(cc1CO)[C@H]1C[C@H](O)[C@@H](CO)O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ewelina Zarakowska, et al. Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice. J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1003-1009.?
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