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5-Hydroxymethyl-2-deoxycytidine
CAS No. 7226-77-9
5-Hydroxymethyl-2-deoxycytidine( —— )
Catalog No. M35230 CAS No. 7226-77-9
5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
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| 5MG | 76 | In Stock |
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| 10MG | 116 | In Stock |
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| 25MG | 202 | In Stock |
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| 50MG | 315 | In Stock |
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| 100MG | 477 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1014 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name5-Hydroxymethyl-2-deoxycytidine
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NoteResearch use only, not for human use.
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Brief Description5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.
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Description5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPARP
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RecptorPARP
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Research Area——
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Indication——
Chemical Information
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CAS Number7226-77-9
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Formula Weight257.24
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Molecular FormulaC10H15N3O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (195.11 mM; Ultrasonic )
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SMILESNc1nc(=O)n(cc1CO)[C@H]1C[C@H](O)[C@@H](CO)O1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ewelina Zarakowska, et al. Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice. J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1003-1009.?
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