SRI-011381

CAS No. 1629138-41-5

SRI-011381( SRI-011381 | SRI 011381 | SRI011381 )

Catalog No. M17348 CAS No. 1629138-41-5

SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 43 In Stock
5MG 61 In Stock
10MG 107 In Stock
25MG 227 In Stock
50MG 346 In Stock
100MG 514 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SRI-011381
  • Note
    Research use only, not for human use.
  • Brief Description
    SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
  • Description
    SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease.
  • In Vitro
    ——
  • In Vivo
    Animal Model:YAPGFAP-CKO mice bearing experimental autoimmune encephalomyelitis (EAE)Dosage:30 mg/kg .Administration:Intraperitoneally injection; every 2 d; for 22 days Result:Significantly inhibited inflammatory infiltration and relieved the loss of neurons in YAPGFAP-CKO EAE mice.
  • Synonyms
    SRI-011381 | SRI 011381 | SRI011381
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1629138-41-5
  • Formula Weight
    329.48
  • Molecular Formula
    C20H31N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (151.75 mM)
  • SMILES
    O=C(NC1=NC2=CC=C(CN3CCC(C(C)(O)C)CC3)C=C2N1[C@H]4CC[C@@H](C(NC(C)C)=O)CC4)C5=CC=C(F)C=C5
  • Chemical Name
    N'-Cyclohexyl-N-(phenylmethyl)-N-(4-piperidinylmethyl)-urea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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