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AZD8542
CAS No. 1126366-36-6
AZD8542( —— )
Catalog No. M34171 CAS No. 1126366-36-6
AZD8542 is an antagonist of Smoothened (SMO) with potential as an [oncology therapeutic].
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 613 | In Stock |
|
| 10MG | 847 | In Stock |
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| 25MG | 1311 | In Stock |
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| 50MG | 1655 | In Stock |
|
| 100MG | 2186 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZD8542
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NoteResearch use only, not for human use.
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Brief DescriptionAZD8542 is an antagonist of Smoothened (SMO) with potential as an [oncology therapeutic].
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DescriptionAZD8542 is an antagonist of Smoothened (SMO), playing an important role in oncology. AZD8542 is a Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetHedgehog (Hh)
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RecptorHedgehog/Smoothened | Smo
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Research Area——
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Indication——
Chemical Information
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CAS Number1126366-36-6
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Formula Weight412.48
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Molecular FormulaC25H24N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=CC(C=2N=CN(C2)C)=C(C=C1C)C)C3=CC=C(OCC4=NC=CC=C4)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rosa F. Hwang, INHIBITION OF THE HEDGEHOG PATHWAY TARGETS THE TUMOR-ASSOCIATED STROMA IN PANCREATIC CANCER. Mol Cancer Res. 2012 Sep; 10(9): 1147–1157.
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