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BRD9526

CAS No. 1446352-30-2

BRD9526( BRD 9526 )

Catalog No. M11897 CAS No. 1446352-30-2

BRD9526 is a potent, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 60 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BRD9526
  • Note
    Research use only, not for human use.
  • Brief Description
    BRD9526 is a potent, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 60 nM.
  • Description
    BRD9526 is a potent, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 60 nM, partially lowers Gli1 expression at concentrations of 10 uM, a useful probe of Shh signaling pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BRD 9526
  • Pathway
    GPCR/G Protein
  • Target
    Hedgehog (Hh)
  • Recptor
    Hedgehog (Hh)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1446352-30-2
  • Formula Weight
    584.509
  • Molecular Formula
    C26H31Cl2N3O6S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Cyclopropanecarboxamide, N-[(2R,3S)-2-[[[(2,4-dichlorophenyl)sulfonyl]methylamino]methyl]-3,4,5,6-tetrahydro-5-[(1R)-2-hydroxy-1-methylethyl]-3-methyl-6-oxo-2H-1,5-benzoxazocin-10-yl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schaefer GI, et al. J Am Chem Soc. 2013 Jul 3;135(26):9675-80.
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