Cart
sales@molnova.com
Phorbol 12,13-dibutyrate
CAS No. 37558-16-0
Phorbol 12,13-dibutyrate( —— )
Catalog No. M33465 CAS No. 37558-16-0
Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that inhibits α1-adrenoceptor-mediated positive inotropic effects in a concentration-dependent manner, induced by contraction of isolated rabbit vascular smooth muscle.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 180 | In Stock |
|
| 5MG | 163 | In Stock |
|
| 10MG | 282 | In Stock |
|
| 25MG | 560 | In Stock |
|
| 50MG | 855 | In Stock |
|
| 100MG | 1358 | In Stock |
|
| 200MG | 1832 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePhorbol 12,13-dibutyrate
-
NoteResearch use only, not for human use.
-
Brief DescriptionPhorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that inhibits α1-adrenoceptor-mediated positive inotropic effects in a concentration-dependent manner, induced by contraction of isolated rabbit vascular smooth muscle.
-
DescriptionPhorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator and a potent skin tumor promoter.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetPKC
-
RecptorPKC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number37558-16-0
-
Formula Weight504.61
-
Molecular FormulaC28H40O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 125 mg/mL (247.72 mM)
-
SMILES[H][C@]12[C@]3([H])C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@]4([H])[C@@]3(O)[C@H](C)[C@@H](OC(=O)CCC)[C@@]1(OC(=O)CCC)C2(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Singh J, et al. Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G317-25.?
molnova catalog
related products
-
Solamargine
Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cells.
-
(±)-1,2-Diolein
(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein increases myotubes Ca 2+ influx .
-
Hypocrellin A
Hypocrellin A is PKC inhibitor has light-induced antitumorantifungal and antiviral activities it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.
