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Phorbol 12,13-dibutyrate
CAS No. 37558-16-0
Phorbol 12,13-dibutyrate( —— )
Catalog No. M33465 CAS No. 37558-16-0
Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that inhibits α1-adrenoceptor-mediated positive inotropic effects in a concentration-dependent manner, induced by contraction of isolated rabbit vascular smooth muscle.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 180 | In Stock |
|
| 5MG | 163 | In Stock |
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| 10MG | 282 | In Stock |
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| 25MG | 560 | In Stock |
|
| 50MG | 855 | In Stock |
|
| 100MG | 1358 | In Stock |
|
| 200MG | 1832 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePhorbol 12,13-dibutyrate
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NoteResearch use only, not for human use.
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Brief DescriptionPhorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that inhibits α1-adrenoceptor-mediated positive inotropic effects in a concentration-dependent manner, induced by contraction of isolated rabbit vascular smooth muscle.
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DescriptionPhorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator and a potent skin tumor promoter.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC
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Research Area——
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Indication——
Chemical Information
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CAS Number37558-16-0
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Formula Weight504.61
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Molecular FormulaC28H40O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 125 mg/mL (247.72 mM)
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SMILES[H][C@]12[C@]3([H])C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@]4([H])[C@@]3(O)[C@H](C)[C@@H](OC(=O)CCC)[C@@]1(OC(=O)CCC)C2(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Singh J, et al. Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G317-25.?
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