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PROTAC BRD4 ligand-1

CAS No. 2313230-51-0

PROTAC BRD4 ligand-1( —— )

Catalog No. M33078 CAS No. 2313230-51-0

PROTAC BRD4 ligand-1, a component of Protac GNE-987, is a ligand for BRD4 and acts as an inhibitor of BET.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	297	In Stock
10MG	496	In Stock
25MG	938	In Stock
50MG	1544	In Stock
100MG	2223	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
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Biological Information

Product Name

PROTAC BRD4 ligand-1
Note

Research use only, not for human use.
Brief Description

PROTAC BRD4 ligand-1, a component of Protac GNE-987, is a ligand for BRD4 and acts as an inhibitor of BET.
Description

PROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Epigenetic Reader Domain
Recptor

Epigenetic Reader Domain | Ligands for Target Protein for PROTAC
Research Area

——
Indication

——

Chemical Information

CAS Number

2313230-51-0
Formula Weight

500.47
Molecular Formula

C23H18F2N4O5S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 5 mg/mL (9.99 mM; Ultrasonic )
SMILES

Cn1cc2-c3cc(CS(C)(=O)=O)c(cc3N(Cc3c[nH]c(c23)c1=O)c1ncc(F)cc1F)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.?

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